刘金华

来源 :      作者 : admin     时间 : 2012-08-02     点击次数 : 4956

刘金华

刘金华,男,1964年10月出生,浙江桐庐人,中共党员,理学博士,教授,教育部学位与研究生教育评估专家。分别就读于杭州师范学院、杭州大学和浙江大学。杭州师范大学教授、硕士生导师,先后担任人事处副处长、党委人才办副主任、组织部副部长、人事处处长,现任钱江学院院长兼党委副书记,浙江省“151”第三层次、杭州市“131”第二层次培养人选。主要从事微流控芯片加工工艺和微流控基因分析芯片等领域的研究工作,主持国家自然科学基金面上项目2项、浙江省自然科学基金和浙江省分析测试基金各1项、浙江省重大科技创新团队(项目号2010R50017)子项目和长江学者和创新团队发展计划(项目号IRT 1231)培育项目各一项。作为主要创始人之一建立了杭州师范大学“微流控分析芯片研究所”,为进一步开展相关的科学研究创造了良好的平台。已在玻璃基片上研制了连续PCR微芯片并成功扩增了500bp l DNA片段;建立了微流控芯片与等离子体质谱联机系统并用于生物分析;建立了液相色谱-等离子体质谱联用系统用于汞和碘形态分析。先后获省自然科学优秀论文奖2项,浙江省高校科研成果二等奖1项。在Journal of Chromatography A、Analyst、Electrophoresis、Journal of Analytical Atomic Spectrometry、Spectrochimica Acta Part B、Synlett、Tetrahedron、Analytical Methods、Material Research Bulletin、Current Pharmaceutical Design、European Physical Journal D、分析化学、高等学校化学学报、中国科学-化学、化学进展等国内外学术刊物上已经正式发表学术论文40余篇,其中SCI收录近30篇。

电子邮件:jinhua6903@163.com

【获奖情况】

1.“新试剂2-[2/-(6/-甲基-苯并噻唑)偶氮]-5-二甲氨基苯甲酸的酸碱平衡及其与铜(Ⅱ)显色反应的研究” 浙江省自然科学优秀论文 二等奖,第二作者;

2.“新试剂2-[2/-(6/-甲基-苯并噻唑)偶氮]-5-二甲氨基苯甲酸与Fe(Ⅱ)显色反应研究”浙江省自然科学优秀论文三等奖,第一作者。

【主要科研项目及角色】

1.“微流控芯片-毛细管电泳-微液滴喷射雾化器等离子体质谱联机进行单细胞内金属形态分析的研究”国家自然科学基金,80万元,主持人,2013.1-2016.12;

2.“阵列芯片电泳-等离子体质谱联用研究金属-生物分子的相互作用”浙江省分析测试基金,3万元,主持人,2014.1-2015.12;

3.“芯片电色谱-等离子体质谱联用的应用研究”浙江省重大科技创新团队(项目号2010R50017)子课题,5万元,主持人,2013.1-2014.12

4.“芯片电泳-等离子体质谱研究钌抗癌药的代谢规律”长江学者和创新团队发展计划(项目号IRT 1231)培育项目,4万元,主持人,2013.5-2015.4

5.“微流控芯片技术及其快速测定病原体方法的研究”国家自然科学基金 26万元,主持人,2007.1-2009.12;

6.“新型PCR-CE集成微流控基因分析芯片的研究”浙江省自然科学基金5.5万元,主持人,2003.1-2005.12;

7.浙江省高校中青年学科带头人,4万元,浙江省教育厅,2007-2010;

8.“杭州市131人才第二层次”,5万元,杭州市人事局,2003-2008;

9.“浙江省151人才第三层次”,浙江省人事厅,2005-2008。

【代表性论著】

1. Chao Han, Jiannan Sun, Jinhua Liu, Heyong Cheng*, Yuanchao Wang, A pressure-driven capillary electrophoretic system with injection valve sampling, Analyst, 2015, 140(1), 162-173.

2. Jiannan Sun, Dan Wang, Heyong Cheng*, Jinhua Liu*, Yuanchao Wang, Zigang Xu, Use of ion-pairing reagent for improving iodine speciation analysis in seaweed by pressure-driven capillary electrophoresis and ultraviolet detection, J. Chromatogr. A, 2015, 1379, 112-117.

3. Heyong Cheng, Chunling Wu, Jinhua Liu*, Zigang Xu, Thiol-functionalized silica microspheres for online preconcentration and determination of mercury species in seawater by high performance liquid chromatography and inductively coupled plasma mass spectrometry, RSC Adv., 2015, 5, 19082-19090.

4. Heyong Cheng*, Chunling Wu, Lihuan Shen, Jinhua Liu, Zigang Xu, Online anion exchange column preconcentration and high performance liquid chromatographic separation with inductively coupled plasma mass spectrometry detection for mercury speciation analysis, Anal. Chim. Acta, 2014, 828, 9-16.

5. Chao Han, Jiannan Sun, Heyong Cheng*, Jinhua Liu, Zigang Xu, Speciation analysis of urine iodine by ion-pair reversed-phase high performance liquid chromatography and inductively coupled plasma mass spectrometry, Anal. Methods, 2014, 6, 5369-5375.

6. Heyong Cheng, Chao Han, Zigang Xu, Jinhua Liu*, Yuanchao Wang, Sensitivity enhancement by field amplified sample injection in interfacing microchip electrophoresis with inductively coupled plasma mass spectrometry for bromine speciation in bread, Food Anal. Methods, 2014, 7, 2153-2162.

7. Xiaopan Chen, Chao Han, Heyong Cheng, Jinhua Liu*, Zigang Xu, Xuefeng Yin, Determination of mercurial species in fish by inductively coupled plasma mass spectrometry with anion exchange chromatographic separation, Anal. Chim. Acta, 2013, 796, 7-13.

8. Zhang L., Zhao Z. L., Wei X. H.*, Liu J. H.*, Preparation and in vitro and in vivo characterization of cyclosporin A-loaded, PEGylated chitosan-modified, lipid-based nanoparticles, International Journal of Nanomedicine, 2013, 8, 601-610.

9. Xiaopan Chen, Chao Han, Heyong Cheng, Yuanchao Wang, Jinhua Liu, Zigang Xu, Lei Hu, Rapid speciation analysis of mercury in seawater and marine fish by cation exchange chromatography hyphenated with inductively coupled plasma mass spectrometry, J. Chromatogr. A, 2013, 1314, 86-93.

10. Chunling Wu, Heyong Cheng*, Jinhua Liu, Zigang Xu*, Xuefeng Yin, Determination of Platinum in Human Plasma by Microchip-based Nanoflow Injection and Inductively Coupled Plasma Mass Spectrometry, Chinese J. Anal. Chem., 2013, 41, 349-353.

11. Rui Huang, Chunsong Xie*, Lin Huang, Jinhua Liu*, A Novel Synthesis of 1,4,7,10-Tetraazacyclododecane by the Tandem Reaction of a Vinylsulfonium Salt, Letters in Organic Chemistry, 2013, 10(3), 195-198.

12. Rui Huang, Chunsong Xie*, Lin Huang, Jinhua Liu*, Copper-catalyzed N-alkoxyalkylation of nucleobases involving direct functionalization of sp3 C-H bonds adjacent to oxygen atoms,Tetrahedron, 2013, 69(2), 577-582.

13. Song X. L., Shen H.*, Yin X. F., Wang X. Z., Liu J. H., Microflow-injection chemiluminescence of luminol and hypochlorite enhanced by phloxine B, Luminescence, 2013, 28(1), 16-22.

14. Xin Ye, Chunsong Xie*, Rui Huang, Jinhua Liu*, Direct synthesis of α-amino amides from N-alkyl amines by the copper-catalyzed oxidative ugi-type reaction, Synlett., 2012, 23(3), 409-412.

15 Han X., Cao L. H., Cheng H. Y.*, Liu J. H., Xu Z. G.*, Determination of iodine species in seaweed and seawater samples using ion-pair reversed phase high performance liquid chromatography coupled with inductively coupled plasma mass spectrometry, Anal. Methods, 2012, 4(10), 3471-3477.

16. Cheng H. Y., Liu J. H., Xu Z. G., Yin X. F.*, A microfluidic sub-microlitre sample introduction system for direct analysis of Chinese rice wine by inductively coupled plasma mass spectrometry using external aqueous calibration, Spectrochim. Acta Part B, 2012, 73(1), 55-61.

17. Cheng H. Y., Liu J. H., Yin X. F.*, Shen H., Xu Z. G., Elimination of suction effect in interfacing microchip electrophoresis with inductively coupled plasma mass spectrometry using porous monolithic plugs, Analyst, 2012, 137(13), 3111-3118.

18. Cheng H. Y., Xu Z. G., Liu J. H., Wang X. Z., Yin X. F.*, A microfluidic system for introduction of nanolitre sample in inductively coupled plasma mass spectrometry using electrokinetic flow combined with hydrodynamic flow, J. Anal. At. Spectrom., 2012, 27(2), 346-353.

19. Bian T. B., Yin X. F.*, Liu J. H., Study on the effect of surfactants on morphologies of trigonal selenium in microfluidic reactor, Mater. Res. Bull., 2010, 45(2), 113-117.

20. Xie C. S., Han D. Y., Hu Y., Liu J. H.*, Xie T.*, Synthesis of pyrrolidin-2-ones via tandem reactions of vinyl sulfonium salts under mild conditions, Tetrahedron Lett., 2010, 51(40), 5238-5241.

21. Hu H. M., Yin X. F.*, Qi L. Y., Liu J. H., Pump-free and low-cost negative pressure sampling device for rapid sample loading in MCE, Electrophoresis, 2009, 30(24), 4213-4218.

22. Qia L. Y., Yin X. F.*, Liu J. H., Rapid and efficient isotachophoretic preconcentration in free solution coupled with gel electrophoresis separation on a microchip using a negative pressure sampling technique, J. Chromatogr., A, 2009, 1216(20), 4510-4516.

23. Xie C. S., Han D. Y., Liu J. H.*, Xie T., Novel syntheses of N-aryloxazolidin-2-ones via tandem reactions of vinyl sulfonium salts, Synlett., 2009, 20(19), 3155-3158.

24. 吴春玲, 程和勇*, 徐子刚, 刘金华, 殷学锋. 芯片纳流动注射-等离子体质谱测定血浆中的铂, 分析化学, 2013, 41(3), 349-353.

25. 叶美英, 周刚, 李宝兴, 刘金华*. 纳米TiO2光催化芳香醛的缩醛反应研究, 中国科学: 化学, 2013, 43(1), 1-7.

26. 郝丽, 程和勇, 刘金华, 殷学锋*, 微流动注射-等离子体质谱直接测定白酒中的铅和镉, 高等学校化学学报, 2012, 33(9), 1957-1963.

27. 郝丽, 徐春秀, 程和勇, 刘金华, 殷学锋*, 微流控芯片测定单细胞内化学组分的进展, 化学进展, 2012, 24(8), 1544-1553.

29. 叶美英, 李宝兴, 叶荣民, 刘金华*.微反应器中二氧化钛/过氧化氢协同光催化降解及其应用, 分析化学, 2010, 38(5), 643-647.